4-Hydroxy-5,6,7,8-tetrahydroquinoline-3-carboxylic acids and der

Details 4-Hydroxy-5,6,7,8-tetrahydroquinoline-3-carboxylic acids and der 4-Hydroxy-5,6,7,8-tetrahydroquinoline-3-carboxylic acids and der

1980-01-29

1981-06-16

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2602391, 424258, C07D21556, C07D49968, A61K 3147

Patent

active

042739322

ABSTRACT:
Disclosed is a quinoline derivative having the general formula ##STR1## where A represents a six-membered hydrocarbon ring; X represents an oxygen atom, an .dbd.NOR.sup.1 group in which R.sup.1 is a hydrogen atom or a lower alkyl radical of from 1 to 5 carbon atoms, a hydroxyl group, or an --NHR.sup.2 group in which R.sup.2 is a hydrogen atom or an acyl group; and Y represents a hydrogen atom, a salt-forming radical, or an ester-forming radical. This quinoline derivative is a novel compound which has antiallergic effects in itself and is useful as an intermediate in the production of penicillin or cephalosporin derivatives.

REFERENCES:
patent: 3864329 (1975-02-01), Tobiki et al.
patent: 3951955 (1976-04-01), Tobiki et al.
patent: 3992371 (1976-11-01), Tobiki et al.
patent: 4005075 (1977-01-01), Yamada et al.
Agui, et al., J. Heterocyclic Chem., 12, pp. 1245-1254 (1975).

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