4-Hydroxy-2-pyrone derivatives having antihyperlipaemic activity

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...

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2603435, C07D30930, A61K 31365

Patent

active

042554446

ABSTRACT:
4-Hydroxy-2-pyrone derivatives of formula (I): ##STR1## (wherein A represents an alkylene group which is optionally alkyl-substituted or an alkenylene group, and Z represents a substituted or unsubstituted aryl or aryloxy group) may be prepared by cyclizing an ester of formula (II): ##STR2## (wherein A and Z are as defined above and R represents an organic group) and have valuable antilipaemic activities.

REFERENCES:
patent: 3983140 (1976-09-01), Endo et al.

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