4-Homoisotwistane-aminoacid amides

Details 4-Homoisotwistane-aminoacid amides 4-Homoisotwistane-aminoacid amides

1979-12-12

1981-07-07

Demers, Arthur P.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424267, 424274, 26032639, 542415, 544154, 544155, 546203, 564164, 564165, 564188, 564189, 564191, 564193, C07C10350, C07C10368, A61K 3116

Patent

active

042774730

ABSTRACT:
Compounds having the formula ##STR1## wherein a is 0 or 1, R.sub.1 is hydrogen or lower alkyl, A is lower alkylene or lower alkylidene, and R.sub.2 and R.sub.3, which can be the same or different, are hydrogen, lower alkyl, cycloalkyl, benzyl or substituted benzyl, or ##STR2## is a saturated heterocyclic ring, and acid addition salts thereof, possess anti-viral activity and reduced activity on the central nervous system.

REFERENCES:
patent: 3919313 (1975-11-01), Villani
patent: 4157342 (1979-06-01), Inamoto
Aigami et al., J. Med. Chem. 19 (1976) pp. 536-540.
Aldrich et al., J. Med. Chem. 14 (1971) pp. 535-543.

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