4-heterocyclophenyl-substituted dihydropyridines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546277, 546281, 514343, C07D40110, A61K 3144

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active

054038499

ABSTRACT:
4-Heterocyclophenyl-substituted dihydropyridines ##STR1## are prepared either by reacting suitable aldehydes with amino esters and .beta.-keto esters, or preparing the heterocyclic substituents of the 4-phenyl by cyclization of corresponding amidines or hydrazides, or esterifying dihydropyridinecarboxylic acids, which are already substituted by heterocyclic radicals, with corresponding alcohols. The 4-heterocyclophenyl-substituted dihydropyridines can be employed in medicaments, in particular for treatment of diseases of the central nervous system.

REFERENCES:
patent: 3488359 (1970-01-01), Bossert et al.
patent: 3574843 (1971-04-01), Bossert et al.
patent: 4406906 (1983-09-01), Meyer et al.
patent: 4510310 (1985-04-01), Wehinger et al.
patent: 4568681 (1986-02-01), Wehinger et al.
patent: 4590276 (1986-05-01), King
patent: 4622332 (1986-11-01), Wehinger et al.
patent: 4727066 (1988-02-01), Sunkel et al.
patent: 4849433 (1989-07-01), Wehinger et al.
patent: 4988717 (1991-01-01), Wehinger et al.
Abstract, 88-283059/40, B03, Fuji Oct. 9, 1986, JP-239353 (Aug. 30, 1988), "Optically Active 1,4-Dihydro:Pyridine Derivatives . . . "; one page.
TIPS, vol. 111, Aug. 1990; I. Izquierdo, "Nimodipine and the Recovery of Memory"; 2 pages.
Can. J. Physiol. Pharmacol., vol. 65, 1987, pp. 1452-1460; D. Rampe et al., "Comparative Aspects and Temperature Dependence of . . . ".

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