4-heteroaryl-3-heteroarylidenyl-2-indolinones and their use...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S323000, C514S316000, C514S321000, C514S300000, C514S253090, C514S318000, C546S201000, C546S187000, C546S197000, C546S113000, C546S194000, C544S130000, C544S364000

Reexamination Certificate

active

07053086

ABSTRACT:
The present invention relates to certain 4-heteroaryl-3-heteroarylidenyl-2-indolinones compounds and their physiologically acceptable salts which modulate the activity of protein kinases (“PKs”), in particular CDK2. The compounds of the present invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical composition containing these compounds and methods of preparing these compounds are also described.

REFERENCES:
patent: 5302606 (1994-04-01), Spada
patent: 6130239 (2000-10-01), Chen et al.
patent: WO 98/07695 (1998-02-01), None
patent: WO 98/50356 (1998-11-01), None
patent: WO 99/61422 (1999-12-01), None
patent: WO 00/35906 (2000-06-01), None
patent: WO 00/35908 (2000-06-01), None
patent: WO 00/35909 (2000-06-01), None
patent: WO 00/35909 (2000-06-01), None
patent: WO 00/56709 (2000-09-01), None
patent: WO 01/60814 (2001-08-01), None

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