4-(Formylthio)azetidinones and ozonization process therefor

Details 4-(Formylthio)azetidinones and ozonization process therefor 4-(Formylthio)azetidinones and ozonization process therefor

1977-05-10

1979-01-09

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260326S, 26032637, 544 16, C07d20508, C07d40312, C07d40304

Patent

active

041338081

ABSTRACT:
Ozonolysis of 3-bromomethyl-2-cephem-4-carboxylic acid esters provides 1-(1-protected carboxy-2-hydroxy-3-bromo-1-propenyl)-3-amido(or imido)-4-formylthio-azetidin-2-ones, useful as intermediates in the preparation of cephalosporin antibiotics.

REFERENCES:
chauvette et al., J. Amer. Chem. Soc. 96, (15); 4986-4987 (1974).

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