4-diazo-3-methyl-2,5-cyclohexadine-1-one and pharmacetically acc

Details 4-diazo-3-methyl-2,5-cyclohexadine-1-one and pharmacetically acc 4-diazo-3-methyl-2,5-cyclohexadine-1-one and pharmacetically acc

1985-12-12

1990-02-27

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Diazo or diazonium

514150, 534558, 534565, 435 41, 435128, 435933, C07C11304, A61K 31665

Patent

active

049047647

ABSTRACT:
4-Diazo-3-methoxy-2,5-cyclohexandien-1-one, and pharmaceutically acceptable salts thereof, are antibiotics having antibacterial activity against a variety of gram positive and gram negative bacteria, particularly against anaerobic bacteria. The compound can be prepared by culturing aerobically Penicillium funiculosum A.T.C.C. No. 20783 in a culture medium containing assimilable sources of carbohydrates and nitrogen.

REFERENCES:
Chem. Ber., vol. 95, pp. 1206-1218, (1962).
Houben-Weyl, Methoden Der Organischen Chemie, Chinondiazide, pp. 353-394, (1979).
Horner et al., Ber. Deut, Chem. Gesell., vol. 95, pp. 1206 to 1218, (1962).
Poskocil et al., Chemical Abstracts, vol. 48, #4221a-t, (1954).

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