4'-Deschlororebeccamycin pharmaceutical composition and method o

Details 4'-Deschlororebeccamycin pharmaceutical composition and method o 4'-Deschlororebeccamycin pharmaceutical composition and method o

1984-09-04

1985-06-18

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 22, 536 24, 435 85, A61K 3171, C12P 1938, C07H 1904

Patent

active

045241457

ABSTRACT:
A new antitumor antibiotic designated herein as 4'-deschlororebeccamycin is produced by fermentation of Nocardia aerocolonigenes ATCC 39243. The new compound possesses antibacterial activity and inhibits the growth of tumors in experimental animals.

REFERENCES:
J. Antibiotics, 30, (4), A New Alkaloid AM-2282 of Steptomyces Origin Taxonomy, Fermentation, Isolation and Preliminary Characterization, S. Omura et al., pp. 275-282, 1977.
J. C. S. Chem. Comm., X-Ray Crystal Structure of Staurosporing: A New Alkaloid from a Streptomyces Strain, A. Furusaki et al., pp. 800-801, 1978.
Angew. Chem. Int. Ed. Engl., 19, (6), Indole Pigments from the Fruiting Bodies of the Slime Mold Arcyria denudata, W. Steglich et al., pp. 459-460, 1980.

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