4-demethoxy-4'-amino-4'-deoxy-anthracycline derivatives

Details 4-demethoxy-4'-amino-4'-deoxy-anthracycline derivatives 4-demethoxy-4'-amino-4'-deoxy-anthracycline derivatives

1990-03-30

1991-09-03

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 64, 536 62, 536 172, A01K 3170, A01N 4308, C07H 1524

Patent

active

050455346

ABSTRACT:
Antitumour anthracycline glycosides of formula I: ##STR1## wherein R.sub.1 is hydrogen or a hydroxyl group, and pharmaceutically acceptable acid addition salts thereof.

REFERENCES:
patent: 4046878 (1977-09-01), Patelli et al.
patent: 4067969 (1978-01-01), Fenco et al.
patent: 4125607 (1978-11-01), Arcamone et al.
patent: 4366149 (1982-12-01), Bargiotti et al.
patent: 4448724 (1984-05-01), Cava et al.
patent: 4522815 (1985-06-01), Bargotti et al.
Arcamone et al., Cancer Treatment Reports, vol. 60, No. 7, Jul. 1976, pp. 829-834.
Sammes (Editor), Topics in Antibiotic Chemistry, vol. 2, 1978, pp. 226 and 227.
Chemical Abstracts 1978, vol. 89, No. 13, Abstract No. 99696d, DeMarco et al., Cancer Treat. Rep., vol. 62, No. 3, pp. 375-380.

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