4-Cyclopropylmethyleneoxy-3-chlorophenylacetic acid and salts th

Details 4-Cyclopropylmethyleneoxy-3-chlorophenylacetic acid and salts th 4-Cyclopropylmethyleneoxy-3-chlorophenylacetic acid and salts th

1975-01-09

1976-08-24

Morgenstern, Norman

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2605011, 26050114, 26050115, 2605012, 260520R, 260999, 424294, 424316, 424317, C07C 6352, C07C 8714, C07F 108

Patent

active

039766730

ABSTRACT:
The compound 4-cyclopropylmethyleneoxy-3-chlorophenylacetic acid and its non-toxic pharmaceutically acceptable salts have activity as anti-inflammatory, antipiretic and analgesic agents. It is prepared by reacting a lower alkyl ester of 3-chloro-4-hydroxyphenyl acetic acid with a cyclopropylmethylene halide and subsequently saponifying the ester obtained. The acid obtained is optionally salified to give corresponding non-toxic, inorganic or organic pharmaceutically acceptable salts.

REFERENCES:
patent: 3553226 (1971-01-01), Kaiser et al.
patent: 3766263 (1973-10-01), Godfrey
patent: 3786085 (1974-01-01), Dickel et al.

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