Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-08-11
2008-11-18
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S262000
Reexamination Certificate
active
07452893
ABSTRACT:
Compounds represented by Formula (I) or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.
REFERENCES:
patent: 4904666 (1990-02-01), Friebe et al.
patent: 5723608 (1998-03-01), Yuan
patent: 2005/0054658 (2005-03-01), Thompson et al.
patent: 0 641 781 (1995-03-01), None
patent: 0 729 758 (1996-09-01), None
patent: WO 98/35048 (1998-08-01), None
patent: WO 01/23389 (2001-04-01), None
Anthony C. Bishop, et al. “Design of allele-specific inhibitors to probe protein kinase signaling” Current Biology, vol. 8, No. 5, 1998, pp. 257-266.
McCauley (Expert Opin. Ther. Patents, 2005, 15(4), 389-407).
Alden, P., HIV and the central nervous system, The Bay Area Reporter, Jun. 16, 2000, <http://www.aegis.org
ews/bar/2000/BR000605.html> dowloaded on Jan. 22, 2007.
Robins, Roland K., J. Am. Chem. Soc., vol. 79, pp. 6407-6415, 1957.
Hamilton, Harriet W., Bristol, James A.: J. Med. Chem., vol. 26, pp. 1601-1606, 1983.
Rideout, Janet L., Krenitsky, Thomas A., Koszalka, George W., Cohn, Naomi K., et al.—J. Med. Chem., vol. 25, pp. 1040-1044, 1982.
Butcher John
Dieckhaus Christine
Layton Mark E.
Liverton Nigel
McCauley John A.
Kifle Bruck
Krovatin William
Merck & Co. , Inc.
Todaro John C.
LandOfFree
4-cycloakylaminopyrazolo pyrimidine NMDA/NR2B antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 4-cycloakylaminopyrazolo pyrimidine NMDA/NR2B antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-cycloakylaminopyrazolo pyrimidine NMDA/NR2B antagonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4033534