4-cyanopiperidine derivatives

Details 4-cyanopiperidine derivatives 4-cyanopiperidine derivatives

1986-07-08

1988-01-26

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21126

Patent

active

047217880

ABSTRACT:
A novel 4-cyanopiperidine derivative, which is represented by the following general formula (I): ##STR1## wherein X means a halogen atom, or an acid addition salt thereof, is prepared by reacting N-(2-hydroxyethyl)-4-carbamoylpiperidine or an acid addition salt thereof with a dehydrating and halogenating agent; or by reacting 4-cyanopiperidine or a salt thereof with a compound represented by the following general formula (IV):

REFERENCES:
patent: 3118926 (1964-01-01), Horrom
patent: 4426386 (1984-01-01), Arvidsson et al.
Noller, "The Chemistry of Organic Compounds", 3rd Ed., (1965), p. 253; [W. B. Saunders Co., Philadelphia & London].

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