4-cyano-3-hydroxybutanoyl hydrazines, derivatives and process fo

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

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558451, C07C24328

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active

061145661

ABSTRACT:
Novel 4-cyano-3-hydroxybutanoyl hydrazides (10), particularly R-chiral intermediates are described. The intermediates are useful in preparing (R)-3-hydroxy-4-trimethylaminobutyric acid (L-carnitine) and R-4-amino-3-hydroxybutyric acid (GABOB) and chiral chemical intermediates which are medically useful.

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