4-Chloro-7-sulphobenzofurazan and salts thereof; new fluorigenic

Details 4-Chloro-7-sulphobenzofurazan and salts thereof; new fluorigenic 4-Chloro-7-sulphobenzofurazan and salts thereof; new fluorigenic

1981-10-13

1982-11-09

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D27108

Patent

active

043585957

ABSTRACT:
New fluorigenic thiol specific reagents, 4-chloro-7-sulphobenzofurazan and salts thereof, are disclosed. The reagents are prepared by sulphonation of 4-chlorobenzofurazan. Ammonium 4-chloro-7-sulphobenzofurazan is used to label glutathione as a model thiol peptide and bovine serum albumin and jackbean urease as thiol containing proteins.

REFERENCES:
patent: 3501285 (1970-03-01), Baldwin
patent: 3524861 (1970-08-01), Hackmann et al.
patent: 4145360 (1979-03-01), Crosby et al.

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