Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-09-07
2000-11-14
Seaman, D. Margaret
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514312, 546159, 546153, A61K 3147, C07D21538, C07D21514
Patent
active
061470902
ABSTRACT:
Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
REFERENCES:
patent: 5231101 (1993-07-01), Honda et al.
patent: 5231102 (1993-07-01), Baker et al.
patent: 5276168 (1994-01-01), Atwal
patent: 5288725 (1994-02-01), Witherup et al.
patent: 5401848 (1995-03-01), Atwal
US application Ser. No. 09/390,731, Filing Date Sep. 7, 1999, Priority Application 60/100,729, Priority Date Sep. 17, 1998.
US application Ser. No. 09/390,738, Filing Date Sep. 7, 1999, Priority Application 60/100,926, Priority Date Sep. 17, 1998.
US application Ser. No. 09/391,152, Filing Date Sep. 7, 1999, Priority Application 60/100,860, Priority Date Sep. 17, 1998.
US application Ser. No. 09/391,313, Filing Date Sep. 7, 1999, Priority Application 60/100,927, Priority Date Sep. 17, 1998.
Chemical Abstracts vol. 116, 1992, 116:151569g.
Chemical Abstracts vol. 123, 1995, 123:55716b.
Gordon DJ, et al., Circulation. 79(1):8-15, Jan. 1989, "High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies".
DeNinno Michael P.
Mularski Christian J.
Ruggeri Roger B.
Wester Ronald T.
Benson Gregg C.
Olson A. Dean
Pfizer Inc.
Richardson Peter C.
Seaman D. Margaret
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