Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1983-10-13
1985-12-03
Berch, Mark L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D20508
Patent
active
045565147
ABSTRACT:
.beta.-Lactam compounds which are useful as intermediates for the production of carbapenem or penem derivatives and a process for producing the same. The process comprises reacting a Schiff base with diketene in the presence of an imidazole, reducing the acetyl group of the resulting N-protected-3-acetyl-2-azetidinone-4-carboxylic acid ester, and removing the protecting group for a carboxyl group from the resulting 3-(1-hydroxyethyl)-2-azetidinone-4-carboxylic acid derivative.
REFERENCES:
Shiozaki et al., Tet. Letters 22, 5205, (1981).
Hirai et al., Tet. Letters 23, 4025, (1982).
Neider et al., Tet. Letters 23, 2293, (1982).
Sankyo et al., Chem. Abs. 94, 103147y, (1980).
Sankyo et al., Chem. Abs. 96, 85334s, (1981).
Sankyo et al., Chem. Abs. 98, 72422k.
Hagemeyer et al., Chem. Abs. 43, 839e, (1949).
Kato et al., Chem. Pharm. Bull. 24, 356, (1976).
Enomoto Masao
Goda Koshiro
Sasaki Akira
Sunagawa Makoto
Berch Mark L.
Sumitomo Chemical Company Limited
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