4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and thei

Details 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and thei 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and thei

1985-09-18

1987-06-16

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07D20508, C07D41702, A61K 31425

Patent

active

046737391

ABSTRACT:
Compounds of the formula ##STR1## are useful as intermediates in preparing 1-sulfo-2-oxoazetidine compounds having the carbamoyloxymethyl group at the 4-position. The final product compounds have antimicrobial and/or .beta.-lactamase-inhibitory activity and are of value as drugs for human beings and domesticated animals.

REFERENCES:
patent: 4200572 (1980-04-01), Gleason et al.
patent: 4225586 (1980-09-01), Imada et al.
patent: 4229436 (1980-10-01), Imada et al.
Imada et al., Nature, vol. 289, pp. 590-591 (1981).
Sykes et al., Nature, vol. 291, pp. 489-491 (1981).
12th International Congress of Chemotherapy, Florence, Italy, Jul. 19-24, 1981, pp. 55-56.
Sykes et al., Journal of Antimicrobial Chemotherapy, (1981) 8 Suppl. E 1-16.
Sykes et al., Chemical Abstracts, 95, 217370S (1981).
Matsuo et al., Chemical Abstracts, 95, 97566M (1981).

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