4-benzylpiperazines useful as neuroleptics

Details 4-benzylpiperazines useful as neuroleptics 4-benzylpiperazines useful as neuroleptics

1987-08-11

1989-05-16

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514248, 514249, 544280, 544281, 544350, 544360, 544368, 544402, A61K 31495, A61K 31505, C07D29502, C07D29504

Patent

active

048310344

ABSTRACT:
Compounds of formula (I) in which the broken line forms a phenyl, naphthyl, pyridyl, indolizine, pyrrolo[1,2-a]pyrazine, pyrrolo[1,2-a]pyrimidine or pyrrolo[1,2-c]pyrimidine ring-system, R=H, halogen, OH, alkyl, alkyloxy or alkylthio, R'=H, halogen, alkyl, alkyloxy, alkylthio, CN or CF.sub.3, n and p=1, 2 or 3, the alkyl radicals having 1 to 4 C in a straight or branched chain.
These products are useful as neuroleptics. ##STR1##

REFERENCES:
Henry, Chem. Abst., vol. 66 (1967), 37889k.
Duncan et al, Chem. Abst., vol. 70(1969), 47401s.
Hasegawa et al, Chem. Abst., vol. 77(1972), 48507n.
Roch et al, Chem. Abst., vol. 89(1978), 6322r.
Hino et al, Chem. Abst., vol. 94(1981), 30538q.
Schoofs et al, Chem. Abst., 101-6860f (1984).
Barreau et al, Chem. Abst. 107-175903b (1987).
Chemical Abstracts, vol. 77, 1972, pp. 496-497-No. 48507n.
Chemical and Pharmaceutical Bulletin, vol. 28, No. 9, 1980, pp. 2618-2622.

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