Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-11-15
2009-06-16
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S252140, C514S275000, C540S575000, C544S295000, C544S331000
Reexamination Certificate
active
07547691
ABSTRACT:
The present invention provides compounds of Formula I: useful in the treatment of cancer and inflammatory diseases.
REFERENCES:
patent: WO 2004/089913 (2004-10-01), None
patent: WO 2006/066172 (2006-06-01), None
Meeting Abstracts, Innovative Rheumatology: Gene and Cell Therapies of Arthritis and Related Autoimmune Disorders Second International Meeting, Arthritis Research 3 (Suppl 1):A1-A16, 2001.
Catley et al., Validation of IKKbeta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery dominant-negative IKKbeta to pulmonary epithelial cells, British Journal of Pharmacology, vol. 145 (1), pp. 114-122, (2005).
Greten et al., IKKbeta Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer, Cell, vol. 118, pp. 285-296, Aug. 6, 2004.
Dahnke Karl Robert
Lin Ho-Shen
Richett Michael Enrico
Shih Chuan
Wang Q May
Eli Lilly and Company
Rao Deepak
Tucker Tina M.
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