4-aryloxy- and 4-arylthiopiperidine derivatives

Details 4-aryloxy- and 4-arylthiopiperidine derivatives 4-aryloxy- and 4-arylthiopiperidine derivatives

1994-07-21

1996-10-01

Chang, Ceila

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546209, A61K 31445, C07D41306

Patent

active

055611451

ABSTRACT:
Novel 4-aryloxy- or 4-arylthiopiperidine derivatives of the formula I ##STR1## in which R.sup.1 and R.sup.2 are each, independently of one another, phenyl radicals which are unsubstituted or mono or disubstituted by A, OH, OA, aryloxy with 6-10 C atoms, aralkyloxy with 7-11 C atoms, --0--(CH.sub.2).sub.n --0--, Hal, CF.sub.3, NO.sub.2, NH.sub.2, NHA, NA.sub.2, NHAc, NAAc, NHSO.sub.2 A and/or NASO.sub.2 A,

REFERENCES:
patent: 4804657 (1989-02-01), Kogure
patent: 4970217 (1990-11-01), Prucher
patent: 5232931 (1993-08-01), Prucher
Duncan et al., "Aroylpiperidines and Pyrrolidines, etc.", Journal of Medicinal Chemistry, vol. 13, No. 1, pp. 1-6, Jan. 1970.

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