4-arylcyclopenta[c]pyrrole analgesics

Details 4-arylcyclopenta[c]pyrrole analgesics 4-arylcyclopenta[c]pyrrole analgesics

1995-05-17

1996-07-30

McKane, Joseph K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548466, 548515, 5462767, A61K 31395, C07D20902

Patent

active

055412173

ABSTRACT:
The 4-arylcyclopenta[c]pyrroles of the following formula are effective analgesics: ##STR1## including stereoisomers and pharmaceutically acceptable salts thereof, wherein ##STR2## with the proviso that the 3a and 6a hydrogens are cis and where there is a 4-position hydroxy then such is trans to the 3a and 6a hydrogens, and

REFERENCES:
patent: 5216018 (1993-06-01), Ciganek
CA 114:6288u Preparation of . . . antibiotics. Ogata et al., p. 619, 1991.

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