Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-08-30
1998-11-17
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142335, 5142338, 514253, 514275, 514337, 514340, 514373, 514374, 514375, 514382, 514397, 514414, 514422, 514456, 540524, 544114, 544133, 544138, 544151, 544238, 544297, 544360, 5462694, 5462751, 5462831, 548112, 548131, 548159, 548190, 548198, 548222, 548236, 548252, 548254, 5482664, 5483051, 548413, 548452, 548525, A01N 4316, A01N 31535, A01N 4364, A01N 4340
Patent
active
058377026
ABSTRACT:
Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein X is alkyl, Y is a single bond, --CH.sub.2 --, --C(O)--, --O--, --S-- or --N(R.sup.8)-- where R.sup.8 is hydrogen, alkyl, haloalkyl, aryl, arylalkyl, cycloalkyl or (cycloalkyl)alkyl, and R.sup.1 to R.sup.7 are as defined herein. These compounds have potassium channel activating activity and are useful, therefore for example, as cardiovascular agents.
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Atwal Karnail S.
Ding Charles Z.
Rovnyak George C.
Santafianos Dinos P.
Almaula Prabodh I.
Bristol-Myers Squibb Co.
Covington Raymond
Kight John
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