4-(Arylaliphatic)isoxazoles

Details 4-(Arylaliphatic)isoxazoles 4-(Arylaliphatic)isoxazoles

1979-09-04

1981-05-19

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424272, 568308, C07D26108, A61K 3142

Patent

active

042686784

ABSTRACT:
4-(Arylaliphatic)isoxazoles, having antiviral activity, are prepared by reacting with hydroxylamine a diketone of the formula Ar-Y-CH(CO-R).sub.2, wherein Ar is substituted phenyl, Y is (CH.sub.2).sub.n or O(CH.sub.2).sub.n, and R is lower-alkyl.

REFERENCES:
patent: 4000150 (1976-12-01), Combon et al.
patent: 4031246 (1977-06-01), Collins et al.
patent: 4093736 (1978-06-01), Collins
patent: 4163057 (1979-07-01), Nadelson
Kochetkov et al., Zhur. Obshchei Chem. 30, 3675-3682 (1960).

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