4-aryl-4-piperidine (or pyrrolidine or hexahydroazepine) carbino

Details 4-aryl-4-piperidine (or pyrrolidine or hexahydroazepine) carbino 4-aryl-4-piperidine (or pyrrolidine or hexahydroazepine) carbino

1989-08-28

1992-02-04

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514299, 514311, 514315, 514317, 514318, 514319, 514330, 514331, A61K 31445, A61K 3144, A61K 3147

Patent

active

050860631

ABSTRACT:
Known and novel 4-aryl-4-piperidinecarbinols and heterocyclic analogs are useful as analgesics. Also provided are novel pyrrolidinecarbinols and hexahydroazepine carbinols which are useful as analgesics, antidepressants and, in some cases, as anorectic agents.

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Bondesson et al., Acta Pharm. Suec., 17, 1 (1980).
Rogers et al., J. Med. Chem., 1980, 23(6), 688-690, "Some Spiro Analogs of the Potent Analgesic Ketobemidone."

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