4-anilinoquinoline-3-carboxamides

Details 4-anilinoquinoline-3-carboxamides 4-anilinoquinoline-3-carboxamides

2006-05-02

2006-05-02

Seaman, D. Margaret (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S159000

Reexamination Certificate

active

07037925

ABSTRACT:
The present invention relates to novel compounds of formula (IA), which are JAK3 Kinase inhibitors, methods for their preparation and pharmaceutical compositions comprising them.

REFERENCES:
patent: WO 9843960 (1998-08-01), None
patent: WO 98/43960 (1998-10-01), None
patent: WO 0010981 (2000-02-01), None
Sen, Chemical Abstracts 34:75700, 1965.
Boschelli, J Med Chem, vol. 44, pp 822-833, 2001.
Vissner, J Med Chem, VOI 43, pp 3244-3256, 2000.
J. Med. Chew., vol. 44, No. 5, Mar. 2001, Diane H. Boschelli et al: “Synthesis and Src Kinase Inhibitory Activity of a Series of 4-Phenylamino-3-quinolinecarbonitriles”, pp.822-833, p. 823, No. 19.
J. Med. Chem., vol. 43, No. 17, 2000, Allan Wissner et al: “4-Anilino-6,7-ialkoxyquinoline-3-carbonitrile Inhibitors of Epidermal Growth Factor Receptor Kinase and Their Bioisosteric Relationship to the 4-Anilino-6,7-dialkoxyquinazoline Inhibitors”, p. 3244 - p. 3256; p. 3249, No. 54; p. 3255, p.3248.
STN Internal, File Ca, CAOLD, accession No. CA64 :14164b, Sen, Achintya K. et al: “Synthesis of 4-aminoquinolines”; J. Indian Chem. Soc. 42(12), 851-4(1965)(Eng)., RN 5382-40-1.

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