4- and 5-Substituted 2,3-dihydro-1H-isoindoles, pharmaceutical c

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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2603261, A61K 3140, C07D20944

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active

042184649

ABSTRACT:
Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase using novel 2,3-dihydro-1H-isoindole compounds having 4- and 5-substituents.

REFERENCES:
C. Grogan, J. Med. Chem. 10(4), pp. 621-623 (1967), omega-Azabicyclic Butyrophenones.
W. Rosen et al., JACS 79, pp. 3167-3174, (1957), Tetrachloroisoindolines and Related Systems.
W. Adcock et al., Chem. Abst. 84: 179060d (1976).
R. Kreher et al., Chem. Abst. 82: 57506s (1975).
J. Bornstein et al., Chem. Abst. 82: 139890b (1975).

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