4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives as...

Details 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives as... 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives as...

2004-01-23

2010-02-16

Coleman, Brenda L (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S260100, C514S252160, C544S117000, C544S278000

Reexamination Certificate

active

07662814

ABSTRACT:
New 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives having the chemical structure of general formula (I), and pharmaceutically acceptable salts thereof are disclosed, as well as processes for their preparation and to pharmaceutical compositions containing them and their use in the treatment, prevention or suppression of pathological conditions, diseases and disorders susceptible of being improved by inhibition of PDE7.

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Martinez, A. et al. “Benzyl Derivatives of 2,1,3-Benzo- and Benzothieno[3,2-a]thiadiazine 2,2-Dioxides: First Phosphodiesterase 7 Inhibitors,”J. Medicinal Chemistry43(4): 683-689 (2000).
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