4-Aminoquinoline derivatives, useful as anti-inflammatory agents

Details 4-Aminoquinoline derivatives, useful as anti-inflammatory agents 4-Aminoquinoline derivatives, useful as anti-inflammatory agents

1979-04-09

1980-11-25

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546160, 546161, C07D21544, A61K 3147

Patent

active

042359082

ABSTRACT:
New 4-aminoquinoline derivatives having the formula ##STR1## wherein X is halogen or trifluoromethyl at the designated 7- or 8-position; Z is hydrogen, halogen, lower alkyl, lower alkoxy, nitro, di(lower alkyl)amino or trifluoromethyl, n is from 1 to 4, R.sup.1 is hydrogen or lower alkyl, R.sup.2 is lower alkyl, R.sup.3 is lower alkyl and A is lower alkylene, and their pharmaceutically acceptable acid addition salts show anti-inflammatory activity.

REFERENCES:
patent: 3376195 (1968-04-01), Allais et al.
patent: 3632761 (1972-01-01), Graham et al.
patent: 3637710 (1972-01-01), Wasley et al.
patent: 3875165 (1975-04-01), Archibald et al.
patent: 3971787 (1976-07-01), Archibald et al.
patent: 3971789 (1976-07-01), Archibald et al.

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