4-Aminopyrimidium derivatives and preparation thereof

Details 4-Aminopyrimidium derivatives and preparation thereof 4-Aminopyrimidium derivatives and preparation thereof

1975-08-08

1977-07-26

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602565R, 424251, C07D23926

Patent

active

040382788

ABSTRACT:
New 4-aminopyrimidium derivatives of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 each represents a hydrogen atom or a lower alkyl group, and R.sub.3 and R.sub.4 each represents a hydrogen or halogen atom, a lower alkyl, a lower alkoxyl, a lower alkoxycarbonyl, a lower alkylsulfonyl, nitro or amino group, and X represents a halogen atom, as well as a process for the preparation thereof. The compounds are useful as anti-inflammatory, analgesic agents without producing gastrointestinal trouble.

REFERENCES:
rodd Chem. of Carbon Compounds, vol. IV, Part A, Heterocyclic Compounds Elsevier (1957), pp. 510 & 511.
Otiai et al., "Chem. Abstracts," vol. 33 (1939), col. 3791.sup.9, Abstract of J. Pharm. Soc., Japan, 59, pp. 18-28 (1939).

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