4-aminobenzoylguanidine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514256, 514331, 514370, 514398, 514399, 514408, 514428, 514603, 514634, 544322, 544332, 546231, 546304, 548196, 5483435, 564 85, 564237, A61K 31505, A61K 31425, C07D23942, C07D27738

Patent

active

057391424

ABSTRACT:
4-Aminobenzoylguanidines of the formula I ##STR1## in which A, R.sub.1, R.sub.2 and R.sub.3 have the meanings given, and the physiologically unobjectionable salts thereof exhibit antiarrhythmic properties and are active as inhibitors of the cellular Na.sup.+ /H.sup.+ antiporter.

REFERENCES:
patent: 5091394 (1992-02-01), Englert et al.
patent: 5292755 (1994-03-01), Englert et al.

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