4-Aminoalkyl-4-cyano-4-phenyl-butanoic acid esters

Details 4-Aminoalkyl-4-cyano-4-phenyl-butanoic acid esters 4-Aminoalkyl-4-cyano-4-phenyl-butanoic acid esters

1974-12-11

1976-12-21

Gotts, Lewis

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

42424854, 42424855, 4242485, 260239B, 2602471R, 2602472A, 2602472B, 260268CN, 260290H, 26029373, 26029375, 26029378, 26032643, 260465D, 424244, 424250, 424267, 424274, A61K 31275, C07C12178

Patent

active

039989658

ABSTRACT:
Alkyl esters, dialkylamides and heterocyclic amides of 4-amino-alkyl-4-cyano-4-phenyl-butanoic and but-2-enoic acids substituted in at least one of the 2 and 3 positions by a C.sub.1 -C.sub.4 alkyl group or by a divalent alkylene radical which together with at least one of the carbon atoms at said 2 and 3 positions forms a carbocyclic ring of 3 to 8 carbon atoms are novel intermediates involved in the preparation of pharmacologically active compounds. They also have pharmacological, in particular central nervous system, especially anti-depressant or cardiovascular activity. Several methods are disclosed for preparing the novel compounds.

REFERENCES:
patent: 3125583 (1964-03-01), Leonard
patent: 3261859 (1966-07-01), Dengel

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