4-amino substituted-6-aryl/heteroaryl...

Details 4-amino substituted-6-aryl/heteroaryl... 4-amino substituted-6-aryl/heteroaryl...

2008-01-01

2008-01-01

Coleman, Brenda (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

active

07314934

ABSTRACT:
Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.

REFERENCES:
patent: 3843663 (1974-10-01), Williams et al.
patent: 4560691 (1985-12-01), Lesher et al.
patent: 4897395 (1990-01-01), Duch et al.
patent: 5409930 (1995-04-01), Spada et al.
patent: 5426110 (1995-06-01), Gossett et al.
patent: 5547954 (1996-08-01), Henrie, II et al.
patent: 5597776 (1997-01-01), Bratz et al.
patent: 5620981 (1997-04-01), Blankley et al.
patent: 5733913 (1998-03-01), Blankley et al.
patent: 5733914 (1998-03-01), Blankley et al.
patent: 5817670 (1998-10-01), Takayama et al.
patent: 5945422 (1999-08-01), Doherty et al.
patent: 6200977 (2001-03-01), Cusing et al.
patent: 6498163 (2002-12-01), Boschelli et al.
patent: 6528513 (2003-03-01), Cusing et al.
patent: 6809199 (2004-10-01), Doherty et al.
patent: 2003/0114671 (2003-06-01), Chen
patent: 2003/0130264 (2003-07-01), Jaen
patent: 2003/0139434 (2003-07-01), Ahmed et al.
patent: 2004/0077641 (2004-04-01), Bretschneider et al.
patent: 2004/0092402 (2004-05-01), Kuragano et al.
patent: 0 278 686 (1988-05-01), None
patent: 1-261306 (1989-10-01), None
patent: 2000-38350 (2000-02-01), None
patent: 20000038350 (2000-02-01), None
patent: 2003/127542 (2003-05-01), None
patent: 1-261306 (1989-10-01), None
patent: WO 95/15952 (1995-06-01), None
patent: WO 95/19774 (1995-07-01), None
patent: WO 95/33750 (1995-12-01), None
patent: WO 97/38992 (1997-10-01), None
patent: WO 98/05661 (1998-02-01), None
patent: WO 98/08846 (1998-03-01), None
patent: WO 98/33798 (1998-08-01), None
patent: WO 99/41253 (1999-08-01), None
patent: WO 00/23444 (2000-04-01), None
patent: WO 00/43374 (2000-07-01), None
patent: WO 01/19828 (2001-03-01), None
patent: WO 01/42243 (2001-06-01), None
patent: WO 01/55147 (2001-08-01), None
patent: WO 02/058695 (2002-08-01), None
Carboni et al.,Gazzetta Chimica Italiana, vol. 97(8) pp. 1262-1273 (1967), structures only.
Carboni et al.,Gazzetta Chimica Italiana, vol. 98(10) pp. 1174-1188 (1968), structures only.
Ferrarini et al.,Journal of Heterocyclic Chemistry, vol. 21(2) pp. 417-419 (1984).
Ferrarini et al.,Journal of Heterocyclic Chemistry, vol. 34(5) pp. 1501-1510 (1997).
Borrel, et al., “An unequivocal Synthesis of 4-amino-1,5,6,8-tetra-hydropyrido . . . ”, Coll. Czech. Chem. Commun., 1996, 61(6) pp. 901-909.
Hurlbert, et al., “Studies on Condensed Pyrimidine Systems . . . ”, J. Med. Chem., 1968, vol. 11, pp. 703-707.
Baker et al., Analogs of Tetrahydrofolic acid . . . , J. Heterocyclic Chem., 1964, vol. 1, pp. 263-270.
Anderson et al., “Pyridopyrimidines. 6. Nucleophilic Substitutions . . . ”, J. Org. Chem., 1977, vol. 42, pp. 993-996.
Schoffstall et al., “Synthesis of 5,6-Dihydropyrido . . . ”, J. Org. Chem., 1971, 36(16), pp. 2385-2387.
Victory et al., “New Synthesis of pyrido 2,3 . . . ”, Heterocycles, 1985, 23(5), pp. 1135-1141.
Victory et al., “Cyclisation of Dinitriles by hyrdogen . . . ”, Heterocycles, 1985, 23(8), pp. 1947-1950.
Victory et al., “Nueva sintesis de pririo . . . ”, AFINIDAD, Mar. 1989, vol. 46, pp. 107-113, structures only.
Kloetzer et al., Monatsh Chem., 1965, vol. 96, p. 1567-1572 (w/translation).
Rewcastle et al., “Tyrosine Kinase Inhibitors . . . ”, Journal of Medicinal Chemistry, 1996 39(6), pp. 1823-1835.
Victory et al., “New Synthesis of Pyrido[2,3-d]pyrimidines. III. Nucleophilic Substitution on 4-Amino-2-halo and 2-Amino-4-halo-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-ones”, J. Heterocycl. Chem, 1988, vol. 25, pp. 245-247.
Nishikawa et al., “Structure-Activity Relationships of the Diuretic Activity of Triaza- and Tetraaza- naphthalen Compounds”, Chemical Pharm. Bull., 1976, vol. 24(9), pp. 2057-2077.
Kasparec, et al., Tetrahedron Letters 44 (24) 4567-70 (2003).
Santilli, et al., Journal of Heterocuclic Chemistry, vol. 8(3) pp. 445-453 (1971).

Affiliated with

Also associated with

Rating

4-amino substituted-6-aryl/heteroaryl... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-amino substituted-6-aryl/heteroaryl..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-amino substituted-6-aryl/heteroaryl... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2803129