4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic a

Details 4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic a 4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic a

1975-11-03

1976-11-30

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602472R, 2602472B, 260268TR, 260310R, 424248, 424250, C07D48704

Patent

active

039948935

ABSTRACT:
New 4-amino derivatives of pyrazolo[1,5-a]quinoxaline-3-carboxylic acid, esters and their salts have the formula ##SPC1##
R.sub.1 is hydrogen, lower alkyl or a salt forming ion;
R.sub.2 and R.sub.3 each is hydrogen, lower alkyl, cyclolower alkyl, phenyl, substituted phenyl, phenyl-lower alkylene, di-lower alkylamino-lower alkylene or R.sub.2 and R.sub.3 together with the nitrogen form an unsubstituted or substituted 5- or 6-membered nitrogen heterocyclic in which an additional nitrogen or oxygen may be present.
R.sub.4 is hydrogen, lower alkyl or halogen.
The new compounds are useful as anti-inflammatory agents.

REFERENCES:
burger et al., Medicinal Chem., 3rd Ed. pp. 1588-1589 (1971).
Eudokimo H. et al., Chem. Abs. 55, 5517c (1960).

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