4-amino derivatives of 2-oxo-1-azetidinesulfonic acid salts

Details 4-amino derivatives of 2-oxo-1-azetidinesulfonic acid salts 4-amino derivatives of 2-oxo-1-azetidinesulfonic acid salts

1981-05-29

1988-03-29

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

548194, 544379, 544383, 549 77, C07D20508, C07D41714, C07D41712, C07D40312

Patent

active

047344962

ABSTRACT:
.beta.-Lactams having a sulfonic acid salt substituent in the 1-position, an acylamino substituent in the 3-position and an --NR.sub.2 R.sub.3 substituent in the 4-position wherein R.sub.2 and R.sub.3 are the same or different and each is ##STR1## or R.sub.2 and R.sub.3 together with the nitrogen atom to which they are attached are ##STR2## R.sub.4 is alkyl, aryl or arylalkyl; and R.sub.5 and R.sub.6 are the same or different and each is hydrogen, halogen, alkyl, alkoxy, alkylthio, alkoxycarbonyl, carboxyl or a carboxyl salt; have antibacterial activity.

REFERENCES:
Clauss et al, Liebigs Ann. Chem., 1974, 539-560.

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