4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives

Details 4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives 4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives

2007-07-17

2007-07-17

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S117000, C544S280000, C514S265100

Reexamination Certificate

active

10485747

ABSTRACT:
The invention relates to 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula I wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives and to the use of such derivatives-alone or in combination with one or more other pharmaceutically active compounds-for the preparation of pharmaceutical compositions for the treatment especially of a proliferative disease, such as a tumour

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Caravatti et al., “Pyrrolo[2,3-d]pyrimidine and Pyrazolo[3,4-d]pyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase,” ACS Symposium series, 796, pp. 231-244 (2001)

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