4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and...

Details 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and... 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and...

2008-09-23

2008-09-23

Coleman, Brenda (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S278000

Reexamination Certificate

active

10489052

ABSTRACT:
Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

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