4-amino-1-piperidylbenzoylguanidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546223, 546224, C07D40112, C07D21198, A61K 31445

Patent

active

054610664

ABSTRACT:
4-amino-1-piperidylbenzoylguanidines of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the given meanings, and also the physiologically compatible salts thereof, exhibit antiarrhythmic properties and act as inhibitors of the cellular Na.sup.+ /H.sup.+ antiporter.

REFERENCES:
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patent: 5292755 (1994-03-01), Englert et al.
patent: 5296485 (1994-03-01), Lubish et al.
patent: 5364868 (1994-11-01), Englert et al.
patent: 5395826 (1995-03-01), Naumann et al.
Ishida, Chemical Abstracts, vol. 63, No. 10, Nov. 8, 1965, pp. 13718-13719.

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