Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-06-19
1982-05-25
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602395, 2603973, 26023955R, A61K 3158, C07J 1700
Patent
active
043316638
ABSTRACT:
4.alpha.,5.alpha.-Epoxy-3,20-dioxopregnane-2.alpha.,16.alpha.-dicarbonitril e is prepared by decyclizing 4.alpha.,5.alpha.-epoxy-20-oxopregn-2-eno-[2,3-d]isoxazole-16.alpha.-carbo nitrile with strong base and is useful as an inhibitor of mineralocorticoid production and/or action without concomitant glucocorticoid inhibition in primates.
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patent: 3135743 (1964-06-01), Clinton et al.
patent: 3296255 (1967-01-01), Clinton et al.
patent: 3960842 (1976-06-01), Hoffer et al.
Begue, Gustafsson and Goldman, Endocrinology, vol. 95, pp. 238-246, 1974.
Goldman and Sheth, Biochimica et Biophysica Acta, vol. 315, pp. 233-249, 1973.
Bell Malcolm R.
Christiansen Robert G.
Schane, Jr. Harry P.
Miller Theodore C.
Roberts Elbert L.
Sterling Drug Inc.
Wyatt B. Woodrow
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