Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-12-08
1996-07-16
Kumar, Shailendra
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514279, 514280, 514284, 514285, 514287, 514290, 514297, 546 33, 546 34, 546 35, 546 36, 546 38, 546 39, 546 41, 546 42, 546 47, 546 49, 546 61, 546 62, 546 64, 546 79, 546 80, 546 89, 546105, 546106, A61K 3144, C07D491048
Patent
active
055367283
ABSTRACT:
A novel 4-acylaminopyridine derivative represented by the following formula (I) is disclosed. ##STR1## The 4-acylaminopyridine derivative of the present invention is useful as a medicine for treating disturbances of memory such as senile dementia and Alzheimer's disease, since it has an action of directly activating malfunctioned cholinergic neuron.
REFERENCES:
patent: 4880819 (1989-11-01), Ninomiya et al.
patent: 4985430 (1991-01-01), Morita et al.
G. M. Steinberg et al., "A Hydrophobic Binding Site In Acetylcholinesterase", Journal of Medicinal Chemistry, Nov. 1975, pp. 1056-1061.
Bessho Tomoko
Harada Haruko
Morinaka Yasuhiro
Ninomiya, deceased Kunihiro
Saito Ken-Ichi
Kumar Shailendra
Mitsubishi Chemical Corporation
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