4-Acyl-2,6-dioxo-1-phenethyl piperozines

Details 4-Acyl-2,6-dioxo-1-phenethyl piperozines 4-Acyl-2,6-dioxo-1-phenethyl piperozines

1983-01-31

1985-06-11

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544344, 544382, 544384, 546139, 546145, 546146, 546147, C07D24108

Patent

active

045230137

ABSTRACT:
2-Acyl-1,3,4,6,7,11b-hexahydro-2H-pyrazino-[2,1-a]-4-isoquinoleinones having anthelmintic activity of the formula ##STR1## are prepared from 4-acyl-2,6-dioxopierazines by reaction with a phenethyl halide, selective reduction of one of the oxo groups and cyclization, by the novel intermediates of formula ##STR2## in which Y represents O or H, OH.

REFERENCES:
patent: 3171837 (1965-03-01), Freed
patent: 3239582 (1966-03-01), von Bebenburg et al.
patent: 3969316 (1976-07-01), Ramey et al.
Irikura, "Chemical Abstracts", vol. 84, 1976, Col. 180288r; 180889s.

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