4,7-Disubstituted indoles and methods of making

Details 4,7-Disubstituted indoles and methods of making 4,7-Disubstituted indoles and methods of making

2005-06-14

2005-06-14

Shameem, Golam M M (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S452000, C548S469000, C548S491000

Reexamination Certificate

active

06906096

ABSTRACT:
The present invention provides, compounds, methods and compositions of biologically important indoles. In addition, the present invention provides synthesis methods for substituting leaving groups at positions 4 and 7 of the indole ring as diversity generating elements.

REFERENCES:
patent: 4238486 (1980-12-01), Jones
patent: 5486525 (1996-01-01), Summers et al.
patent: 6040331 (2000-03-01), Yamamoto et al.
patent: WO 2004/014294 (2004-02-01), None
Alper, P. et al., “Practical synthesis and elaboration of methyl 7-chloroindole-4-carboxylate” J. Org. Chem. 68(5):2051-2053 (2003) & Database HCAPLUS on STN, No. 2003:98290 Abstracts.

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