4,7-diacyloxybenzofuran derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514320, 514422, 514452, 514456, 514469, 514470, 546196, 548525, 549362, 549398, 549435, 549466, 549467, 549470, A61K 3134, C07D30782, C07D30780, C07D30779

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049121316

ABSTRACT:
4,7-Diacyloxybenzofuran derivatives of Formula I, are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders, inflammation, psoriasis and allergic conjunctivitis. The compounds are also useful as analgesics and as cytoprotective agents. ##STR1##

REFERENCES:
patent: 4663347 (1987-05-01), Atkinson et al.
Wagner et al., Synthetic Org. Chem., Wiley & Sons, pp. 154-155 and pp. 481-483 (1953).

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