4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S255050, C514S256000, C514S343000, C544S008000, C544S053000, C544S056000, C544S060000, C544S063000, C544S067000, C544S096000, C544S141000, C544S180000, C544S182000, C544S212000, C544S238000, C544S335000, C544S336000, C544S353000, C546S279100

Reexamination Certificate

active

10494127

ABSTRACT:
Novel anti-viral agents of Formulawherein:A represents OR1, NR1R2, or R1wherein R1and R2are hydrogen, C1-6alkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; or R1and R2together with the nitrogen atom to which they are attached form a 5 or 6 membered saturated cyclic group;B represents C(O)R3wherein R3is C1-6alkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl;C represents C1-6alkyl, aryl, heteroaryl or heterocyclyl;D represents a saturated or unsaturated optionally substituted 6-membered heterocyclic ring;E represents hydrogen or C1-6alkyl;F represents hydrogen, C1-6alkyl, aryl or heteroaryl; andG represents hydrogen, C1-6alkyl, heterocyclylalkyl, arylalkyl or heteroarylalkyl; and salts, solvates and esters thereof, processes for their preparation and methods of using them in HCV treatment are provided.

REFERENCES:
patent: 395007 (1992-08-01), None
patent: WO93 18765 (1993-09-01), None
patent: WO99 54299 (1999-10-01), None
patent: WO 01 28996 (2001-04-01), None

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