4,6-Diaryl-pyrimidin-2(1H)-ones as tranquilizers

Details 4,6-Diaryl-pyrimidin-2(1H)-ones as tranquilizers 4,6-Diaryl-pyrimidin-2(1H)-ones as tranquilizers

1975-03-24

1976-05-25

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 31505

Patent

active

039594718

ABSTRACT:
The invention discloses compounds of the class of 1-substituted-4,6-diaryl-pyrimidin-2(1H)-ones, e.g. 1-alkyl-4,6-diphenyl-pyrimidin-2(1H)-ones. The disclosure also includes the preparation of the pyrimidin-2(1H)-ones by oxidation of the corresponding dihydro derivatives and by cyclization of a dibenzoylmethane with an N-alkyl-urea. Utility as pharmaceutical agents such as tranquilizers, sleep-inducers and anti-inflammatory agents is also disclosed.

REFERENCES:
chem. Abst. 69-77211b 1968.

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