4,6-Di-O-(aminoglycosyl)-1,3-diaminocyclitols, process for their

Details 4,6-Di-O-(aminoglycosyl)-1,3-diaminocyclitols, process for their 4,6-Di-O-(aminoglycosyl)-1,3-diaminocyclitols, process for their

1978-06-06

1980-02-26

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 4, A61K 3171, C07H 1522

Patent

active

041907221

ABSTRACT:
The invention includes selectively acylated or sulphenylated 4,6-O-(aminoglycosyl)-1,3-diaminocyclitols (and methods for their preparation). Also included in the invention are 1-N-acylated-derivatives, such as 1-N-formyl-sisomicin, useful because of the anti-bacterial effects (and methods for their procurement). The invention includes, furthermore, methods for the procurement of said 1-N-acylated or sulphenylated derivatives, compositions containing them and methods for their use.

REFERENCES:
patent: 3929762 (1975-12-01), Umezawa et al.
patent: 4029882 (1977-06-01), Wright
patent: 4048430 (1977-09-01), Cooper et al.
patent: 4060682 (1977-11-01), Umezawa et al.
patent: 4065615 (1977-12-01), Horii et al.

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