4,5-trimethylene-4-isothiazoline-3-ones and their use as a bacte

Details 4,5-trimethylene-4-isothiazoline-3-ones and their use as a bacte 4,5-trimethylene-4-isothiazoline-3-ones and their use as a bacte

1983-07-27

1987-11-24

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544168, 548209, 564189, A61K 31425, C07D27504

Patent

active

047089598

ABSTRACT:
A 4,5-trimethylene-4-isothiazoline-3-one of the formula ##STR1## wherein R.sub.1 represents (i) hydrogen, (ii) alkyl having 1-12 carbon atoms, (iii) alkyl having 2 or 3 carbon atoms and substituted by one or two hydroxy groups, (iv) alkenyl having 3 to 6 carbon atoms, (v) ##STR2## wherein n is 0 or 1, m is 1 or 2, R.sup.1 is hydrogen or lower alkyl having from 1 to 5 carbon atoms and R.sub.2 is hydrogen, lower alkyl, nitro, trifluoromethyl or halogen, (vi) cycloalkyl having 3 to 6 carbon atoms and (vii) ##STR3## wherein R.sub.3 is hydrogen, alkyl having 1-12 carbon atoms or ##STR4## defined above, or the salt thereof with a mineral or organic acid. These compounds are useful as bactericides or fungicides.

REFERENCES:
patent: 3562283 (1971-02-01), Lewis et al.
patent: 3761488 (1973-09-01), Lewis et al.
patent: 3950349 (1976-04-01), Buckley et al.

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