4,5-Methano-bufadienolide-rhamnosides, their preparation, and dr

Details 4,5-Methano-bufadienolide-rhamnosides, their preparation, and dr 4,5-Methano-bufadienolide-rhamnosides, their preparation, and dr

1979-09-06

1980-12-30

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugate includes potentiator; or composition comprising...

536 5, 536 6, A61K 31705, C07J 1900

Patent

active

042423325

ABSTRACT:
4,5-methano-bufadienolide-rhamnosides of the formula I ##STR1## where R.sup.1 is hydrogen or alkyl or acyl of 1 to 4 carbon atoms, R.sup.2 and R.sup.3 are identical or different and each is hydrogen or alkyl or acyl of 1 to 4 carbon atoms, or both together are ##STR2## where R.sup.4 and R.sup.5 are identical or different and each is hydrogen or alkyl or alkoxy of 1 or 2 carbon atoms.
The novel compounds may be used for counteracting cardiac insufficiency.

REFERENCES:
patent: 3726857 (1973-04-01), Kubinyi
patent: 3919191 (1975-11-01), Haede et al.

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