4',5'-Dihydro-antibiotic AX-127B-1; 2'-N-des-.beta.-lysyl-4',5'-

Details 4',5'-Dihydro-antibiotic AX-127B-1; 2'-N-des-.beta.-lysyl-4',5'- 4',5'-Dihydro-antibiotic AX-127B-1; 2'-N-des-.beta.-lysyl-4',5'-

1980-11-10

1982-07-06

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424181, 435 80, 536 168, A61K 3171, C07H 1522

Patent

active

043383092

ABSTRACT:
4',5'-Dihydro-antibiotic AX-127B-1, 2'-N-des-.beta.-lysyl-4',5'-dihydro-antibiotic AX-127B-1, the 4-N-acyl and alkyl derivatives thereof and their pharmaceutically acceptable salts. The compounds are useful as antibiotics and as intermediates for preparing the corresponding 3-O-demethyl derivatives of antibiotic AX-127B-1.

REFERENCES:
patent: 4091032 (1978-05-01), Tadanier et al.
patent: 4145253 (1979-03-01), Iida et al.
patent: 4187299 (1980-02-01), Post
patent: 4241182 (1980-12-01), Takasawa et al.
patent: 4283529 (1981-11-01), Rosenbrook, Jr.
Rinehart, Jr. et al., "Aminocyclitol Antibiotics", 1980, pp. 309-320.
Tadanier et al., "Carbohydrate Research", vol. 79, pp. 91-102, vol. 85, pp. 61-71, 1980.

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