4,5-dihydro-3(2H)-pyridazinones and their pharmacological use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142268, 5142278, 5142305, 514247, 514252, 514253, 540488, 544 54, 544 582, 544 584, 544 586, 544 92, 544238, 544239, A61K 31535, C07D41304

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active

048164542

ABSTRACT:
Substituted 4,5-dihydro-3(2H)-pyridazinones of the formula I ##STR1## wherein R, for example, denotes a radical of the formula ##STR2## R.sup.1 and R.sup.2, for example, denote hydrogen or methyl, R.sup.3, for example, denotes 2-methoxy-ethoxy, 3-pyridyl-methoxy, amino-carbonyl-methoxy, hydroxy-carbonyl-methoxy, methyl-thio, (2-methoxy-ethyl)-amino-carbonyl-methoxy, 3-pyridyl-methyl or 5-methyl-1,3,4-oxadiazol-2-yl and R.sup.4, for example, denotes hydrogen, have useful pharmacological properties and can therefore be used for the preparation of pharmacological products.

REFERENCES:
patent: 4360672 (1982-11-01), Parg et al.
patent: 4361563 (1982-11-01), Austel et al.
patent: 4404203 (1983-09-01), Sircar
patent: 4551455 (1985-11-01), Hilboll et al.
patent: 4666902 (1987-05-01), Zoller et al.

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