4,5-Didehydro-6-hydrox y-2-arylmethoxymethyl-4.alpha.-tetrahydro

Details 4,5-Didehydro-6-hydrox y-2-arylmethoxymethyl-4.alpha.-tetrahydro 4,5-Didehydro-6-hydrox y-2-arylmethoxymethyl-4.alpha.-tetrahydro

1977-04-04

1978-07-11

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30922

Patent

active

041001770

ABSTRACT:
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.

REFERENCES:
patent: 4018804 (1977-04-01), Schneider
patent: 4020173 (1977-04-01), Kelly et al.
patent: 4048194 (1977-09-01), Nelson

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